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Divalproex (Divalproex Sodium) - monitoring more than 16,000 patients
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What does it do?

This product is used for the treatment of epilepsy, migraine and mania. It is believed to exert its effect by increasing gamma-aminobutyric acid (GABA) levels in the brain.

Last text update: 2011-10-05

Last data update: 2012-01-14

Black Box Warning:
This product has a black box warning relating to its increased risk of liver damage, birth defects and pancreatitis.

General Information:

7.4
Divalproex Average Satisfaction Score
  • 81% of patients are at least somewhat satisfied with Divalproex.
  • 35% of patients wish they were told more before they started taking Divalproex

MediGuard regularly polls our more than 16,000 users taking Divalproex (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM). This feedback is continuously updated for the benefit of the MediGuard community. To request scores for specific patient subgroups, please contact research@mediguard.org.

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Global Patient Feedback for Divalproex (Divalproex Sodium)

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My 29 year old son is on 1500mg of depakote er a day along with along with valium, haldol, cogentin, vit. B 6, magnesium. He is a non verbal autistic man with self abusive and aggressive behaviors. Since the new drug regime he is in constant distress making the saddest sounds, breaks my heart. This is new he use to smile but the SIB and aggression have been helped. Could the distress be a side effect of the depakote? Please let me know so we can help him….Thank You

  • 29 year old – Source: MediGuard
  • Posted: 2012-01-28 17:11:17
Reply

I took Depakote for twenty years; it was a wonderful medication. A few years ago I developed Parkinsonism; a very troublesome disorder. A top neurologist in Asheville NC diagnosed my illness. I was titrated down from Depakote and I experienced little or no symptoms of Parkinsonism. With Sinimet being taken presently, I continue to live a relatively normal life. Have a blessed holiday. 12/25/11.

  • 69 year old – Source: MediGuard
  • Posted: 2011-12-25 00:00:17
Reply

I have taken Depakote for 20 years and it has been the only drug that completely controsl my seizures. I am able to lead a normal life and drive. The only complaint: weight gain and increased appetite -- I tried to go off it and my appetite was much less and the weight came off effortlessly. However, it didn't control my seizures. My doc also says I have to be concerned about increased risk of osteoporosis so be sure to take steps to prevent this.

  • 50 year old – Source: MediGuard
  • Posted: 2011-10-19 02:40:55
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DISCLAIMER: MediGuard is not intended to be a substitute for professional medical advice. MediGuard cannot and does not take into consideration every possible interaction or account for individual responses to medicine. Different individuals may respond to medication in different ways. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective, or appropriate for any given patient. Always seek the advice of a qualified health provider with any questions you may have before making any changes to your treatment. The use of the MediGuard site and its content is at your own risk. The MediGuard site and the information contained in it is intended for users in the United States and information in other countries may be different.

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