Safety Alerts & Recalls

What does this mean?

It is important to avoid drawing too many conclusions from these new studies without first speaking with your doctor and reviewing your specific benefits and risks from your proton pump inhibitor medicine. For many patients, the benefits of PPIs will continue to outweigh the risks. If you need to continue taking a PPI for your chronic condition, please also ask your doctor about how you can make changes to your lifestyle to lower your risk of side effects.

If you are taking the over-the-counter medicines Losec (omeprazole) and have not talked to your doctor about your heartburn, indigestion, or acid reflux, please make an appointment with your doctor to discuss your symptoms and the use of this medication.

Proton Pump Inhibitors (PPIs) May Be Linked to Bone Fractures and Bacterial Infections

In this week's Archives of Internal Medicine, two new studies report that medicines known as proton pump inhibitors (PPIs) appear to be associated with bone fractures in postmenopausal women and with higher rates of bacterial infections.

Proton pump inhibitors suppress acid in the stomach and are used to treat certain types of stomach ulcers, Gastro-oesophageal reflux disease (GORD) and other conditions affecting the oesophagus. Medicines in this class include esomeprazole (Nexium), lansoprazole (Zoton), omeprazole (Losec), pantoprazole (Protium), or rabeprazole (Pariet). Losec and its generic omeprazole is also sold over-the-counter to treat frequent heartburn.

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Source: MediGuard CRT
Publication Date: 2010-05-12
Last Updated: 2010-11-08
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