Abitrexate (Methotrexate)

Overview ( 9,000 members taking Abitrexate )

This product is used primarily in the treatment of cancers, rheumatoid arthritis, and psoriasis. It works by interfering with DNA synthesis, repair, and replication which primarily affects rapidly changing cells.

Black Box Warning:
This product has a black box warning relating to its risks in pregnancy, its potentially fatal toxicities of lung, liver, skin, and GI systems, its increased risk of secondary lymphoma and opportunistic infections.
Risk Ratings
Low Risk
General Risk
Elevated Risk
High Risk
On Hold

What is your Risk Rating for this medicine?

The risk of serious side effects for taking this medicine can be different if you take other medicines or if you suffer from a condition. Get your Risk Rating by creating a profile in a few steps.


  • We monitor your health and alert you to any safety updates and recalls.
  • You get to talk directly to other members about their experience.
  • You can create profiles for you and your loved ones.
Create my Profile Learn more about Risk Ratings

Drug Interaction

We check for possible drug-drug or drug-condition interactions for your medical treatment so you know when there is an issue. Drug interactions may create serious side effects that you want to discuss with your doctor.

Register to check interactions
Share your story Share your story! Tell us how MediGuard has helped you or someone you love. Mobile graphic Download the MediGuard Mobile App to manage your prescription and over-the-counter medications, for free. Registration Info Taking multiple medications puts you at risk for possible drug-drug interactions Registration Info Monitor the medical treatment of you and your loved ones.